Search on: DIPEPTIDYL-PEPTIDASE IV INHIBITORS 
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Descriptor English:   Dipeptidyl-Peptidase IV Inhibitors 
Descriptor Spanish:   Inhibidores de Dipeptidil-Peptidasa IV 
Descriptor Portuguese:   Inibidores da Dipeptidil-Peptidase IV 
Synonyms English:   Gliptins  
Tree Number:   D27.505.519.389.745.335
Definition English:   Compounds that supress the degradation of INCRETINS by blocking the action of DIPEPTIDYL-PEPTIDASE IV. This helps to correct the defective INSULIN and GLUCAGON secretion characteristic of TYPE 2 DIABETES MELLITUS by stimulating insulin secretion and suppressing glucagon release. 
History Note English:   2008 
Allowable Qualifiers English:  
administration & dosage adverse effects
agonists analysis
blood cerebrospinal fluid
chemistry classification
chemical synthesis contraindications
diagnostic use economics
history immunology
isolation & purification metabolism
pharmacology pharmacokinetics
poisoning radiation effects
supply & distribution standards
toxicity therapeutic use
urine  
Record Number:   52843 
Unique Identifier:   D054873 

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